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Article

The evolutionary dynamics of influenza A virus adaptation to mammalian hosts

4 Feb 2013

Abstract excerpt

Few questions on infectious disease are more important than understanding how and why avian influenza A viruses successfully emerge in mammalian populations, yet little is known about the rate and nature of the virus' genetic adaptation in new hosts. Here, we measure, for the first time, the genomic rate of adaptive evolution of swine influenza viruses (SwIV) that originated in birds. By using a curated dataset...

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PMID: 23382435
DOI: 10.1098/rstb.2012.0382

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