Article
Viremia, resuppression, and time to resistance in human immunodeficiency virus (HIV) subtype C during first-line antiretroviral therapy in South Africa.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Dec 2009
Hoffmann Christopher J, Charalambous Salome, Sim John, Ledwaba Joanna, Schwikkard Graham, Chaisson Richard E, Fielding Katherine L, Churchyard Gavin J, Morris Lynn, Grant Alison D
Abstract excerpt
BACKGROUND: Episodes of viremia are common in African antiretroviral therapy (ART) programs. We sought to describe viremia, resuppression, and accumulation of resistance during first-line combination ART (cART) in South Africa. METHODS: Retrospective analysis of a cohort receiving zidovudine, lamivudine, and either efavirenz or nevirapine with human immunodeficiency virus (HIV) RNA monitoring every 6 months. We...
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