The APP A673T frequency differs between Nordic countries.

doi:10.1016/j.neurobiolaging.2015.07.011

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Article

The APP A673T frequency differs between Nordic countries.

Neurobiology of aging - 1 Oct 2015

Mengel-From Jonas, Jeune Bernard, Pentti Tienari, McGue Matt, Christensen Kaare, Christiansen Lene

Abstract excerpt

A coding gene variant A673T (rs63750847) in the APP gene has recently been recognized as a protective variant of late-onset Alzheimer's Disease in a large Icelandic population and has been observed recurrently in populations from Nordic countries. The variant also was related to longevity in the Icelandic population. However, because of the extreme rarity of A673T in non-Nordic populations, the association with...

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PMID: 26239177
DOI: 10.1016/j.neurobiolaging.2015.07.011
PMCID: PMC4562869

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