Article
[Circulating cell-free DNA as biomarker for cancer *header*].
Duodecim; laaketieteellinen aikakauskirja - 1 Jan 2015
Isomursu Aleksi, Kononen Juha, Kuopio Teijo
Abstract excerpt
The rapid accumulation of mutations in cancers and the resulting clonal heterogeneity frequently lead to generation of drug-resistant populations of cancer cells. Examinations requiring a tissue biopsy are invasive, making real-time monitoring of the disease difficult. One alternative to support tissue-based testing is fluid biopsy. Malignant cells release to the patient's circulation DNA, which contains somatic...
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