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Article

Multiscale modelling of palisade formation in gliobastoma multiforme.

Journal of theoretical biology - 21 Oct 2015

Caiazzo Alfonso, Ramis-Conde Ignacio

Abstract excerpt

Palisades are characteristic tissue aberrations that arise in glioblastomas. Observation of palisades is considered as a clinical indicator of the transition from a noninvasive to an invasive tumour. In this paper we propose a computational model to study the influence of the hypoxic switch in palisade formation. For this we produced three-dimensional realistic simulations, based on a multiscale hybrid model,...

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Identifiers

PMID: 26235287
DOI: 10.1016/j.jtbi.2015.07.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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