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Article

'Go or grow': the key to the emergence of invasion in tumour progression?

Mathematical medicine and biology : a journal of the IMA - 1 Mar 2012

Hatzikirou H, Basanta D, Simon M, Schaller K, Deutsch A

Abstract excerpt

Uncontrolled proliferation and abnormal cell migration are two of the main characteristics of tumour growth. Of ultimate importance is the question what are the mechanisms that trigger the progression from benign neoplasms (uncontrolled/autonomous proliferation) to malignant invasive tumours (high migration). In the following, we challenge the currently prevailing view that the emergence of invasiveness is mainly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20610469
DOI: 10.1093/imammb/dqq011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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