Article
Conserved and divergent functions of RcrRPQ in Streptococcus gordonii and S. mutans.
FEMS microbiology letters - 1 Aug 2015
Shields Robert C, Burne Robert A
Abstract excerpt
In the dental caries pathogen Streptococcus mutans, an MarR-like transcriptional regulator (RcrR), two ABC efflux pumps (RcrPQ) and two effector peptides encoded in the rcrRPQ operon provide molecular connections between stress tolerance, (p)ppGpp metabolism and genetic competence. Here, we examined the role of RcrRPQ in the oral commensal S. gordonii. Unlike in S. mutans, introduction of polar or non-polar rcrR...
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