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Article

Constraints on haplotype structure and variable gene frequencies suggest a functional hierarchy within cattle MHC class I.

Immunogenetics - 1 Jun 2012

Codner Gemma F, Birch James, Hammond John A, Ellis Shirley A

Abstract excerpt

Six major histocompatibility complex (MHC) classical class I genes have been identified in cattle, and up to three of these are expressed in variable combinations on different haplotypes. The origin and functional significance of this genetic complexity is unknown. However, an improved assembly of the cattle genome, an expanded database of full-length cDNA sequences and high-resolution frequency data concerning...

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PMID: 22454046
DOI: 10.1007/s00251-012-0612-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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