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Article

Predictive value of STMN1 gene promoter polymorphism (-2166T>C) in patients with advanced NSCLC treated with the combination of platinum compounds and vinorelbine.

Cancer chemotherapy and pharmacology - 1 Sept 2015

Mlak Radosław, Krawczyk Paweł, Ciesielka Marzanna, Homa Iwona, Powrózek Tomasz, Prendecka Monika, Kozioł Piotr, Milanowski Janusz, Małecka-Massalska Teresa

Abstract excerpt

PURPOSE: The combination of platinum compounds and vinorelbine is often used as a first-line treatment in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC), without activating EGFR mutations and ALK rearrangement. Unfortunately, less than half of the patients benefit from chemotherapy. Moreover, majority of patients are exposed to a number of side effects of chemotherapy. Stathmin-1...

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Identifiers

PMID: 26220844
DOI: 10.1007/s00280-015-2831-7
PMCID: PMC4540763

Genes

STMN1
ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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