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Article

Evaluation of variant detection software for pooled next-generation sequence data.

BMC bioinformatics - 29 Jul 2015

Huang Howard W, Mullikin James C, Hansen Nancy F

Abstract excerpt

BACKGROUND: Despite the tremendous drop in the cost of nucleotide sequencing in recent years, many research projects still utilize sequencing of pools containing multiple samples for the detection of sequence variants as a cost saving measure. Various software tools exist to analyze these pooled sequence data, yet little has been reported on the relative accuracy and ease of use of these different programs....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26220471
DOI: 10.1186/s12859-015-0624-y
PMCID: PMC4518579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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