Article

PanVariants: Best Practice for Pangenome-based Variant Calling Pipeline and Framework

2026-04-24

Abstract excerpt

<h4>Background: </h4> Although pangenome references offer richer population diversity compared to linear references, current mainstream pangenome-based variant callers are limited to detecting only known variants stored in the graph. To address this limitation, we developed PanVariants, a novel pipeline designed to improve the detection of both known and novel variants accurately. We systematically evaluated its p...

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Literature Corpus work: 560be827-d7d9-5907-89ca-24b27aa1c7db
DOI: 10.64898/2026.04.22.720142

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