Dynamic metabolic model combined with key enzyme analysis reveals the high lipid synthesis mechanism of Aurantiochytrium sp. mutant strain induced by ARTP.

Abstract excerpt

To address the critical industrial bottlenecks in Aurantiochytrium sp. fermentation, specifically the poor synergy between cell growth and lipid synthesis, as well as the low conversion rate of docosahexaenoic acid (DHA), this study established a technical system combining "malonic acid stress screening" with "ARTP mutagenesis directed breeding." By integrating key metabolic enzyme analysis with dynamic metabolic...

Topics

Join the communities discussing this publication.

• Citric Acid Cycle
• Docosahexaenoic Acids
• FAS gene
• Lipids
• Models, Biological