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Article

Association of Anxiety Symptoms in Offspring of Bipolar Parents with Serotonin Transporter-Linked Polymorphic Region (5-HTTLPR) Genotype.

Journal of child and adolescent psychopharmacology - 1 Aug 2015

Park Min-Hyeon, Sanders Erica, Howe Meghan, Singh Manpreet, Hallmayer Joachim, Kim Eunjoo, Chang Kiki

Abstract excerpt

OBJECTIVE: Offspring of parents with bipolar disorder (BD) have been shown to be at high risk for BD. Anxiety symptoms, even at subclinical levels, have been associated with increased risk for BD in these youth. The s-allele of the serotonin transporter-linked polymorphic region (5-HTTLPR) has been implicated in the pathophysiology of both BD and anxiety disorders and has been associated with pharmacological...

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Identifiers

PMID: 26218602
DOI: 10.1089/cap.2014.0115
PMCID: PMC4545526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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