Article
Psychiatric disorders in preschool offspring of parents with bipolar disorder: the Pittsburgh Bipolar Offspring Study (BIOS).
The American journal of psychiatry - 1 Mar 2010
Birmaher Boris, Axelson David, Goldstein Benjamin, Monk Kelly, Kalas Catherine, Obreja Mihaela, Hickey Mary Beth, Iyengar Satish, Brent David, Shamseddeen Wael, Diler Rasim, Kupfer David
Abstract excerpt
OBJECTIVE: The authors evaluated lifetime prevalence and specificity of DSM-IV psychiatric disorders and severity of depressive and manic symptoms at intake in preschool offspring of parents with bipolar I and II disorders. METHOD: A total of 121 offspring ages 2-5 years from 83 parents with bipolar disorder and 102 offspring of 65 demographically matched comparison parents (29 with non-bipolar psychiatric...
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