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Article

Anxiety disorders and anxiety-related traits and serotonin transporter gene-linked polymorphic region (5-HTTLPR) in adolescents: case-control and trio studies.

Psychiatric genetics - 1 Aug 2014

Bortoluzzi Andressa, Blaya Carolina, Salum Giovanni A, Cappi Carolina, Leistner-Segal Sandra, Manfro Gisele G

Abstract excerpt

The role of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) in anxiety disorder and anxiety-related traits is controversial. Besides this study, few studies have evaluated the triallelic genotype in adolescents. The aim of this study was to investigate whether anxiety disorders and anxiety-related traits are associated with 5-HTTLPR (biallelic and triallelic) in adolescents, integrating both...

Topics

Adolescent
Alleles
Anxiety
Anxiety Disorders
Case-Control Studies
Child
Family
Female
Genetic Predisposition to Disease
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait, Heritable

Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 24842237
DOI: 10.1097/YPG.0000000000000035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24842237-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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