Article
The Genomic Contributions of Avian H1N1 Influenza A Viruses to the Evolution of Mammalian Strains.
PloS one - 1 Jan 2015
Koçer Zeynep A, Carter Robert, Wu Gang, Zhang Jinghui, Webster Robert G
Abstract excerpt
Among the influenza A viruses (IAVs) in wild aquatic birds, only H1, H2, and H3 subtypes have caused epidemics in humans. H1N1 viruses of avian origin have also caused 3 of 5 pandemics. To understand the reappearance of H1N1 in the context of pandemic emergence, we investigated whether avian H1N1 IAVs have contributed to the evolution of human, swine, and 2009 pandemic H1N1 IAVs. On the basis of phylogenetic...
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