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Influenza type A in humans, mammals and birds: Determinants of virus virulence, host‐range and interspecies transmission

13 Jun 2003

Abstract excerpt

The virulence of a virus is determined by its ability to adversely affect the host cell, host organism or population of host organisms. Influenza A viruses have been responsible for four pandemics of severe human respiratory disease this century. Avian species harbour a large reservoir of influenza virus strains, which can contribute genes to potential new pandemic human strains. The fundamental importance of...

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PMID: 12815721
DOI: 10.1002/bies.10303

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