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Article

A novel method for in silico identification of regulatory SNPs in human genome.

Journal of theoretical biology - 21 Feb 2017

Li Rong, Zhong Dexing, Liu Ruiling, Lv Hongqiang, Zhang Xinman, Liu Jun, Han Jiuqiang

Abstract excerpt

Regulatory single nucleotide polymorphisms (rSNPs), kind of functional noncoding genetic variants, can affect gene expression in a regulatory way, and they are thought to be associated with increased susceptibilities to complex diseases. Here a novel computational approach to identify potential rSNPs is presented. Different from most other rSNPs finding methods which based on hypothesis that SNPs causing large...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27908705
DOI: 10.1016/j.jtbi.2016.11.022

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