Article
Mendelian Randomization versus Path Models: Making Causal Inferences in Genetic Epidemiology.
Human heredity - 1 Jan 2015
Ziegler Andreas, Mwambi Henry, König Inke R
Abstract excerpt
OBJECTIVE: The term Mendelian randomization is popular in the current literature. The first aim of this work is to describe the idea of Mendelian randomization studies and the assumptions required for drawing valid conclusions. The second aim is to contrast Mendelian randomization and path modeling when different 'omics' levels are considered jointly. METHODS: We define Mendelian randomization as introduced by...
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