Article
Influence of the PNPLA3 rs738409 Polymorphism on Non-Alcoholic Fatty Liver Disease and Renal Function among Normal Weight Subjects.
PloS one - 1 Jan 2015
Oniki Kentaro, Saruwatari Junji, Izuka Tomoko, Kajiwara Ayami, Morita Kazunori, Sakata Misaki, Otake Koji, Ogata Yasuhiro, Nakagawa Kazuko
Abstract excerpt
In normal weight subjects (body mass index < 25 kg/m2), non-alcoholic fatty liver disease (NAFLD) is likely to coexist with metabolic diseases. The patatin-like phospholipase 3 (PNPLA3) polymorphism rs738409 (c.444C>G) is associated with the risk of NAFLD and/or renal dysfunction; however, the influence of the weight status on the associations remains unknown. We aimed to clarify the associations of the PNPLA3...
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