Article
Evidence of pervasive biologically functional secondary structures within the genomes of eukaryotic single-stranded DNA viruses.
Journal of virology - 1 Feb 2014
Muhire Brejnev Muhizi, Golden Michael, Murrell Ben, Lefeuvre Pierre, Lett Jean-Michel, Gray Alistair, Poon Art Y F, Ngandu Nobubelo Kwanele, Semegni Yves, Tanov Emil Pavlov, Monjane Adérito Luis, Harkins Gordon William, Varsani Arvind, Shepherd Dionne Natalie, Martin Darren Patrick
Abstract excerpt
Single-stranded DNA (ssDNA) viruses have genomes that are potentially capable of forming complex secondary structures through Watson-Crick base pairing between their constituent nucleotides. A few of the structural elements formed by such base pairings are, in fact, known to have important functions during the replication of many ssDNA viruses. Unknown, however, are (i) whether numerous additional ssDNA virus...
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