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Article

Multivariate Meta-Analysis of Genetic Association Studies: A Simulation Study.

PloS one - 1 Jan 2015

Neupane Binod, Beyene Joseph

Abstract excerpt

In a meta-analysis with multiple end points of interests that are correlated between or within studies, multivariate approach to meta-analysis has a potential to produce more precise estimates of effects by exploiting the correlation structure between end points. However, under random-effects assumption the multivariate estimation is more complex (as it involves estimation of more parameters simultaneously) than...

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Identifiers

PMID: 26196398
DOI: 10.1371/journal.pone.0133243
PMCID: PMC4509672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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