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Article

High-Dose Vitamin D3 during Tuberculosis Treatment in Mongolia. A Randomized Controlled Trial.

American journal of respiratory and critical care medicine - 1 Sept 2017

Ganmaa Davaasambuu, Munkhzul Baatar, Fawzi Wafaie, Spiegelman Donna, Willett Walter C, Bayasgalan Purev, Baasansuren Erkhembayar, Buyankhishig Burneebaatar, Oyun-Erdene Sereeter, Jolliffe David A, Xenakis Theodoros, Bromage Sabri, Bloom Barry R, Martineau Adrian R

Abstract excerpt

RATIONALE: Existing trials of adjunctive vitamin D in the treatment of pulmonary tuberculosis (PTB) are variously limited by small sample sizes, inadequate dosing regimens, and high baseline vitamin D status among participants. Comprehensive analyses of the effects of genetic variation in the vitamin D pathway on response to vitamin D supplementation are lacking. OBJECTIVES: To determine the effect of high-dose...

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Identifiers

PMID: 28692301
DOI: 10.1164/rccm.201705-0936OC
PMCID: PMC5620670

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VDR

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