Article
Isolation and characterization of CD105+/CD90+ subpopulation in breast cancer MDA-MB-231 cell line.
International journal of clinical and experimental pathology - 1 Jan 2015
Wang Xueliang, Liu Yunjiang, Zhou Kaixuan, Zhang Geng, Wang Feifei, Ren Jingwen
Abstract excerpt
BACKGROUND: The epithelial-mesenchymal transition (EMT) generates cells with properties of stem cells, if that happened, the stem cell should be with mesenchymal property. This study aimed to identify a group of cells with mesenchymal stem cell (MSC)-like characteristics in breast cancer bone metastatic cell line MDA-MB-231, moreover, the relevance between breast cancer stem cells and the EMT was observed. CD105...
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