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Partial Inhibition of Epithelial-to-Mesenchymal Transition (EMT) Phenotypes by Placenta-Derived DBMSCs in Human Breast Cancer Cell Lines, In Vitro.

Cells - 23 Dec 2024

Basmaeil Yasser, Subayyil Abdullah Al, Kulayb Haya Bin, Kondkar Altaf A, Alrodayyan Maha, Khatlani Tanvir

Abstract excerpt

Stem cell-based therapies hold significant potential for cancer treatment due to their unique properties, including migration toward tumor niche, secretion of bioactive molecules, and immunosuppression. Mesenchymal stem cells (MSCs) from adult tissues can inhibit tumor progression, angiogenesis, and apoptosis of cancer cells. We have previously reported the isolation and characterization of placenta-derived...

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PMID: 39768220
DOI: 10.3390/cells13242131

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