Article
SWGDT: A sliding window-based genotype dependence testing tool for genome-wide susceptibility gene scan.
Journal of biomedical informatics - 1 Oct 2015
Wen Yan, Hao Jingcan, Guo Xiong, Xiao Xiao, Wu Cuiyan, Wang Sen, Yang Tielin, Shen Hui, Chen Xiangding, Tan Lijun, Tian Qing, Deng Hong-Wen, Zhang Feng
Abstract excerpt
Genome-wide association studies (GWAS) are a powerful tool for pathogenetic studies of complex diseases. The rich genetic information of GWAS data is mostly not fully utilized. In this study, we developed a sliding window-based genotype dependence testing tool SWGDT. SWGDT can be applied to GWAS data for genome-wide susceptibility gene scan utilizing known causal gene information. To evaluate the performance of...
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