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Article

Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndrome.

Annals of the rheumatic diseases - 1 May 2016

Miceli-Richard Corinne, Wang-Renault Shu-Fang, Boudaoud Saida, Busato Florence, Lallemand Céline, Bethune Kevin, Belkhir Rakiba, Nocturne Gaétane, Mariette Xavier, Tost Jörg

Abstract excerpt

BACKGROUND: Beyond genetics, epigenetics alterations and especially those related to DNA methylation, play key roles in the pathogenesis of autoimmune diseases such as primary Sjögren's syndrome (pSS) and systemic lupus erythematosus. This study aimed to assess the role of methylation deregulation in pSS pathogeny through a genome-wide methylation approach. PATIENTS AND METHODS: 26 female patients with pSS and 22...

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Share to B-Lymphocyte Subsets
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to CpG Islands

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 26183421
DOI: 10.1136/annrheumdis-2014-206998
PMCID: PMC4853580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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