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Identification of novel genes associated with dysregulation of B cells in patients with primary Sjögren’s syndrome

22 Jun 2020

Abstract excerpt

Abstract Background The aim of this study was to identify the molecular mechanism of dysregulation of B cell subpopulations of primary Sjögren’s syndrome (pSS) at the transcriptome level. Methods We enrolled patients with pSS ( n = 6) and healthy controls (HCs) ( n = 6) in the discovery cohort using microarray and pSS ( n = 14) and HCs ( n = 12) in the validation cohort using quantitative PCR (qPCR). Peripheral B...

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PMID: 32571405
DOI: 10.1186/s13075-020-02248-2

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