Article
Differentiation Kinetics of Blood Monocytes and Dendritic Cells in Macaques: Insights to Understanding Human Myeloid Cell Development.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2015
Sugimoto Chie, Hasegawa Atsuhiko, Saito Yohei, Fukuyo Yayoi, Chiu Kevin B, Cai Yanhui, Breed Matthew W, Mori Kazuyasu, Roy Chad J, Lackner Andrew A, Kim Woong-Ki, Didier Elizabeth S, Kuroda Marcelo J
Abstract excerpt
Monocyte and dendritic cell (DC) development was evaluated using in vivo BrdU pulse-chase analyses in rhesus macaques, and phenotype analyses of these cells in blood also were assessed by immunostaining and flow cytometry for comparisons among rhesus, cynomolgus, and pigtail macaques, as well as African green monkeys and humans. The nonhuman primate species and humans have three subsets of monocytes,...
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