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Article

Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression.

Protein science : a publication of the Protein Society - 1 Oct 2015

Bale Jacob B, Park Rachel U, Liu Yuxi, Gonen Shane, Gonen Tamir, Cascio Duilio, King Neil P, Yeates Todd O, Baker David

Abstract excerpt

We recently reported the development of a computational method for the design of coassembling multicomponent protein nanomaterials. While four such materials were validated at high-resolution by X-ray crystallography, low yield of soluble protein prevented X-ray structure determination of a fifth designed material, T33-09. Here we report the design and crystal structure of T33-31, a variant of T33-09 with...

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Identifiers

PMID: 26174163
DOI: 10.1002/pro.2748
PMCID: PMC4594668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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