Article
Inter- and intraserotypic variation in the Streptococcus pyogenes Rgg regulon.
FEMS microbiology letters - 1 Jul 2008
Dmitriev Alexander V, McDowell Emily J, Chaussee Michael S
Abstract excerpt
Human isolates of Streptococcus pyogenes, a Gram-positive bacterium, are characterized by significant genetic and phenotypic variation. The rgg locus, also known as ropB, is a global transcriptional regulator of genes associated with metabolism, stress responses, and virulence in S. pyogenes strain NZ131 (serotype M49). To assess the breadth of the Rgg regulon, the rgg gene was inactivated in three additional...
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