Article
RHCE*ceAG (254C>G, Ala85Gly) is prevalent in blacks, encodes a partial ce-phenotype, and is associated with discordant RHD zygosity.
Transfusion - 1 Nov 2015
Westhoff Connie M, Vege Sunitha, Hipsky Christine Halter, Horn Trina, Hue-Roye Kim, Keller Jessica, Velliquette Randall, Lomas-Francis Christine, Chou Stella T, Reid Marion E
Abstract excerpt
BACKGROUND: RHCE*ceAG has the nucleotide change c.254C>G, which encodes p.Ala85Gly associated with altered expression of e antigen. We analyzed serologic and DNA-based testing data on samples with RHCE*ceAG to determine its effect on antigen expression, linkage with RHD, and its prevalence in African Americans. STUDY DESIGN AND METHODS: Serologic testing was performed by standard methods. Genomic DNA was used for...
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