Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pan-cancer analysis of TCGA data reveals notable signaling pathways

13 Jul 2015

Abstract excerpt

BACKGROUND: A signal transduction pathway (STP) is a network of intercellular information flow initiated when extracellular signaling molecules bind to cell-surface receptors. Many aberrant STPs have been associated with various cancers. To develop optimal treatments for cancer patients, it is important to discover which STPs are implicated in a cancer or cancer-subtype. The Cancer Genome Atlas (TCGA) makes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioinformatics and Genomic Networks
Share to Cancer Genomics and Diagnostics
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26169172
DOI: 10.1186/s12885-015-1484-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pan-cancer analysis of TCGA data reveals notable signaling pathwaysPMID 26169172Read ↗

Integration of multiple networks and pathways identifies cancer driver genes in pan-cancer analysisSemantic proximity Read ↗

PICS: Pathway Informed Classification System for cancer analysis using gene expression dataSemantic proximity Read ↗

A comprehensive overview of oncogenic pathways in human cancerSemantic proximity Read ↗

Common pathways and functional profiles reveal underlying patterns in Breast, Kidney and Lung cancersSemantic proximity Read ↗

Investigate the relevance of major signaling pathways in cancer survival using a biologically meaningful deep learning modelSemantic proximity Read ↗

Functional synergies yet distinct modulators affected by genetic alterations in common human cancers.Semantic proximity Read ↗

Identifying dysregulated pathways in cancers from pathway interaction networksSemantic proximity Read ↗

Pan-cancer analysis of pathway-based gene expression pattern at the individual level reveals biomarkers of clinical prognosisSemantic proximity Read ↗

Integrative analysis revealed a correlation of PIAS family genes expression with prognosis, immunomodulation and chemotherapySemantic proximity Read ↗

A pan-cancer analysis of prognostic genesSemantic proximity Read ↗

Intersectionality in cancer network: Strategies to the identification of therapeutic targetsSemantic proximity Read ↗

CTpathway: a CrossTalk-based pathway enrichment analysis method for cancer researchSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.