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Integrative analysis revealed a correlation of PIAS family genes expression with prognosis, immunomodulation and chemotherapy

25 Mar 2024

Abstract excerpt

BACKGROUND: Protein inhibitor of activated STATs (PIAS) has pleiotropic biological effects, such as protein post-translational modification, transcriptional coregulation and gene editing. It is reported that PIAS family genes are also correlated with immune cells infiltration in cancers that highlights their unnoticed biological role in tumor progression. However, the relationship of their expression with...

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Ferroptosis and cancer prognosis
interferon and immune responses
Ubiquitin and proteasome pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38528630
DOI: 10.1186/s40001-024-01795-7

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