Article
High recombination potential of subtype A HIV-1.
Virology - 1 Oct 2015
Nikolaitchik Olga, Keele Brandon, Gorelick Robert, Alvord W Gregory, Mazurov Dmitriy, Pathak Vinay K, Hu Wei-Shau
Abstract excerpt
Recombination can assort polymorphic alleles to increase diversity in the HIV-1 population. To better understand the recombination potential of subtype A HIV-1, we generated viruses containing sequences from two variants circulating in Russia and analyzed the polymerase gene (pol) of the recombinants after one round of HIV-1 replication using single-genome sequencing. We observed that recombination occurred...
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