Article
High Expression of p62 Protein Is Associated with Poor Prognosis and Aggressive Phenotypes in Endometrial Cancer.
The American journal of pathology - 1 Sept 2015
Iwadate Reiko, Inoue Jun, Tsuda Hitoshi, Takano Masashi, Furuya Kenichi, Hirasawa Akira, Aoki Daisuke, Inazawa Johji
Abstract excerpt
High expression of SQSTM1/p62 (p62) protein, which functions as a hub of oncogenic signaling pathways, has been detected in several human cancers. However, the clinicopathological and functional contribution of p62 expression is largely unknown in endometrial cancers (ECs). In this study, we assessed the expression status of p62 in primary ECs (n = 194) by immunohistochemistry and analyzed its clinical...
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