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Article

Ly6Chigh Monocytes Protect against Kidney Damage during Sepsis via a CX3CR1-Dependent Adhesion Mechanism.

Journal of the American Society of Nephrology : JASN - 1 Mar 2016

Chousterman Benjamin G, Boissonnas Alexandre, Poupel Lucie, Baudesson de Chanville Camille, Adam Julien, Tabibzadeh Nahid, Licata Fabrice, Lukaszewicz Anne-Claire, Lombès Amélie, Deterre Philippe, Payen Didier, Combadière Christophe

Abstract excerpt

Monocytes have a crucial role in both proinflammatory and anti-inflammatory phenomena occurring during sepsis. Monocyte recruitment and activation are orchestrated by the chemokine receptors CX3CR1 and CCR2 and their cognate ligands. However, little is known about the roles of these cells and chemokines during the acute phase of inflammation in sepsis. Using intravital microscopy in a murine model of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to CX3C Chemokine Receptor 1

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Source

Open in PubMed Open full text

Identifiers

PMID: 26160897
DOI: 10.1681/ASN.2015010009
PMCID: PMC4769199

Genes

CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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