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Article

Adaptive evolution of Escherichia coli inactivated in the phosphotransferase system operon improves co-utilization of xylose and glucose under anaerobic conditions.

Applied biochemistry and biotechnology - 1 Feb 2011

Balderas-Hernández Victor Emmanuel, Hernández-Montalvo Verónica, Bolívar Francisco, Gosset Guillermo, Martínez Alfredo

Abstract excerpt

Modification of the phosphoenolpyruvate/sugar phosphotransferase system (PTS) has shown improvement in sugar coassimilation in Escherichia coli production strains. However, in preliminary experiments under anaerobic conditions, E. coli strains with an inactive PTS and carrying pLOI1594, which encodes pyruvate decarboxylase and alcohol dehydrogenase from Zymomonas mobilis, were unable to grow. These PTS⁻ strains...

Read the complete abstract on PubMed

Topics

Anaerobiosis
Culture Techniques
Escherichia coli
Ethanol
Glucose
Kinetics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Mutation

Operon

Phenotype

Phosphoenolpyruvate Sugar Phosphotransferase System

Xylose

Source

Identifiers

PMID: 20740380
DOI: 10.1007/s12010-010-9056-3

Genes

PTS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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