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Article

Fine Tuning of a Type 1 Interferon Antagonist.

PloS one - 1 Jan 2015

Urin Victoria, Levin Doron, Sharma Nanaocha, Harari Daniel, Schreiber Gideon

Abstract excerpt

Type I interferons are multi-potent cytokines that serve as first line of defense against viruses and other pathogens, posses immunomudolatory functions and elicit a growth inhibitory response. In recent years it has been shown that interferons are also detrimental, for example in lupus, AIDS, tuberculosis and cognitive decline, highlighted the need to develop interferon antagonists. We have previously developed...

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Source

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Identifiers

PMID: 26158644
DOI: 10.1371/journal.pone.0130797
PMCID: PMC4497658

Genes

IFNAR1
IFNAR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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