Article
Correlation of matrix metalloproteinase-2 single nucleotide polymorphisms with the risk of small vessel disease (SVD).
Journal of the neurological sciences - 15 Sept 2015
Zhang Min, Zhu Wusheng, Yun Wenwei, Wang Qizhang, Cheng Maogang, Zhang Zhizhong, Liu Xinfeng, Zhou Xianju, Xu Gelin
Abstract excerpt
BACKGROUND: Maladjustment of matrix metalloproteinases (MMPs) results in cerebral vasculature and blood-brain barrier dysfunction, which is associated with small vessel disease (SVD). This study was to aim at evaluating correlations between matrix metalloproteinase-2 and 9 single nucleotide polymorphisms and the risk of SVD. METHODS: A total of 178 patients with SVD were enrolled into this study via Nanjing...
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