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Article

The renin-angiotensin-aldosterone system in cerebral small vessel disease.

Journal of neurology - 1 Jul 2008

Brenner David, Labreuche Julien, Pico Fernando, Scheltens Philip, Poirier Odette, Cambien François, Amarenco Pierre

Abstract excerpt

INTRODUCTION: Cerebral small vessel disease (SVD) appears on magnetic resonance imaging (MRI) as leukoaraiosis (LA), état criblé (EC), and multiple lacunar infarctions (MLI). Although the pathophysiology of SVD is poorly understood, there is evidence of a genetic contribution. We sought to analyze the influence of the renin-angiotensin-aldosterone system (RAAS) on SVD in symptomatic patients from the Génétique de...

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Identifiers

PMID: 18446309
DOI: 10.1007/s00415-008-0816-8

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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