Article
Polymorphisms in the precursor microRNAs and aflatoxin B1-related hepatocellular carcinoma.
Molecular carcinogenesis - 1 Jun 2016
Long Xi-Dai, Huang Xiao-Ying, Yao Jin-Guang, Liao Pinhu, Tang Yu-Jin, Ma Yun, Xia Qiang
Abstract excerpt
The altered expression of some microRNAs (miRNAs) is observed in hepatocellular carcinoma (HCC); however, the genetic polymorphisms in the precursor miRNAs (pre-miRNAs) in aflatoxin B1 (AFB1)-related HCC have not yet been investigated. A hospital-based case-control study, including 1,706 HCC cases and 2,270 controls without any liver diseases or tumors, was conducted in a high AFB1 exposure area of China to...
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