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Article

Genetic polymorphisms in DNA repair genes XRCC4 and XRCC5 and aflatoxin B1-related hepatocellular carcinoma.

Epidemiology (Cambridge, Mass.) - 1 Sept 2013

Long Xi-Dai, Zhao Dong, Wang Chao, Huang Xiao-Ying, Yao Jin-Guang, Ma Yun, Wei Zhong-Hua, Liu Min, Zeng Li-Xiao, Mo Xiao-Qiang, Zhang Jian-Jun, Xue Feng, Zhai Bo, Xia Qiang

Abstract excerpt

BACKGROUND: Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity and may play an important role in carcinogenesis. We investigated the role of genetic polymorphisms at XRCC4 codon 247 (rs3734091, XRCC4P) and XRCC5 codon 180 (rs80309960, XRCC5P) in liver cancer (hepatocellular carcinoma) caused by aflatoxin B1 (AFB1). METHODS: A hospital-based case-control study,...

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Identifiers

PMID: 23788213
DOI: 10.1097/EDE.0b013e31829d2744

Genes

XRCC4
XRCC5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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