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Article

Identification of large variation in pfcrt, pfmdr-1 and pfubp-1 markers in Plasmodium falciparum isolates from Ethiopia and Tanzania.

Malaria journal - 8 Jul 2015

Golassa Lemu, Kamugisha Erasmus, Ishengoma Deus S, Baraka Vito, Shayo Alex, Baliraine Frederick N, Enweji Nizar, Erko Berhanu, Aseffa Abraham, Choy Angel, Swedberg Göte

Abstract excerpt

BACKGROUND: Plasmodium falciparum resistance to anti-malarials is a major drawback in effective malaria control and elimination globally. Artemisinin-combination therapy (ACT) is currently the key first-line treatment for uncomplicated falciparum malaria. Plasmodium falciparum genetic signatures at pfmdr-1, pfcrt, and pfubp-1 loci are known to modulate in vivo and in vitro parasite response to ACT. The objective...

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Identifiers

PMID: 26152336
DOI: 10.1186/s12936-015-0783-3
PMCID: PMC4495614

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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