Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical isolates of uncomplicated falciparum malaria from high and low malaria transmission areas show distinct pfcrt and pfmdr1 polymorphisms in western Ethiopia.

Malaria journal - 3 Jun 2023

Tadele Geletta, Jawara Aminata, Oboh Mary, Oriero Eniyou, Dugassa Sisay, Amambua-Ngwa Alfred, Golassa Lemu

Abstract excerpt

BACKGROUND: Pfcrt gene has been associated with chloroquine resistance and the pfmdr1 gene can alter malaria parasite susceptibility to lumefantrine, mefloquine, and chloroquine. In the absence of chloroquine (CQ) and extensive use of artemether-lumefantrine (AL) from 2004 to 2020 to treat uncomplicated falciparum malaria, pfcrt haplotype, and pfmdr1 single nucleotide polymorphisms (SNPs) were determined in two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Chloroquine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethiopia

Share to Malaria

Share to Malaria, Falciparum

Share to Multidrug Resistance-Associated Proteins

Share to Plasmodium falciparum

Share to Protozoan Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 37270589
DOI: 10.1186/s12936-023-04602-6
PMCID: PMC10239113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical isolates of uncomplicated falciparum malaria from high and low malaria transmission areas show distinct pfcrt and pfmdr1 polymorphisms in western Ethiopia.PMID 37270589Read ↗

Clinical isolates of uncomplicated falciparum malaria from high and low malaria transmission areas show distinct pfcrt and pfmdr1 polymorphisms in western EthiopiaSemantic proximity Read ↗

Identification of large variation in pfcrt, pfmdr-1 and pfubp-1 markers in Plasmodium falciparum isolates from Ethiopia and Tanzania.Semantic proximity Read ↗

Transmission dynamics of co-endemic Plasmodium vivax and P. falciparum in Ethiopia and prevalence of antimalarial resistant genotypes.Semantic proximity Read ↗

Rising antimalarial drug resistance pfcrt K76T and pfmdr1 N86Y gene mutations in Ethiopia: A Systematic Review and Meta-AnalysisSemantic proximity Read ↗

High prevalence of Pfcrt 76T and Pfmdr1 N86 genotypes in malaria infected patients attending health facilities in East Shewa zone, Oromia Regional State, Ethiopia.Semantic proximity Read ↗

Plasmodium falciparum transmission in the highlands of Ethiopia is driven by closely related and clonal parasitesSemantic proximity Read ↗

<i>Plasmodium falciparum</i> transmission in the highlands of Ethiopia is driven by closely related and clonal parasitesSemantic proximity Read ↗

Incidence of kelch13 and Pfmdr1 gene mutations associated with antimalarial drug resistance in Plasmodium falciparum isolates from Ethiopia: a systematic review and meta-analysis.Semantic proximity Read ↗

Decoding Ethiopia’s unique and structurally divergent <i>Plasmodium falciparum</i> populations using genomicsSemantic proximity Read ↗

Genetic diversity of Plasmodium falciparum isolates from patients with uncomplicated and severe malaria based on msp-1 and msp-2 genes in Gublak, North West Ethiopia.Semantic proximity Read ↗

High prevalence of pfcrt-CVIET haplotype in isolates from asymptomatic and symptomatic patients in south-central Oromia, EthiopiaSemantic proximity Read ↗

Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.