Article
Genomic analysis reveals independent evolution of Plasmodium falciparum populations in Ethiopia.
Malaria journal - 4 Mar 2021
Abera Deriba, Kibet Caleb K, Degefa Teshome, Amenga-Etego Lucas, Bargul Joel L, Golassa Lemu
Abstract excerpt
BACKGROUND: Plasmodium falciparum parasite populations in Ethiopia have been experiencing local selective pressures from drugs and immunity, leading to evolutionary adaptation. However, there was a paucity of data on genomic characterization and evolutionary adaptations of P. falciparum isolates from the central area of Ethiopia. METHODS: Whole-genome analysis of 25 P. falciparum isolates from central Ethiopia,...
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