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Clinical isolates of uncomplicated falciparum malaria from high and low malaria transmission areas show distinct pfcrt and pfmdr1 polymorphisms in western Ethiopia

2023-01-04

Abstract excerpt

<h4>Background: </h4> Chloroquine which was the first-line drug for the treatment of uncomplicated P. falciparum malaria in Ethiopia was officially abandoned in 1998, and replaced by sulphadoxine-pyrimethamine which in turn was replaced by artemether-lumefantrine (AL) in 2004. Pfcrt gene has been associated with chloroquine resistance and pfmdr1 gene can alter malaria parasite susceptibility to most of the current...

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Literature Corpus work
5fee3d9d-89f7-517b-b303-02f6e21ebc28
DOI
10.21203/rs.3.rs-2427399/v1
Open publication

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Clinical isolates of uncomplicated falciparum malaria from high and low malaria transmission areas show distinct pfcrt and pfmdr1 polymorphisms in western EthiopiaDOI 10.21203/rs.3.rs-2427399/v1
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