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Article

MicroRNA-431 accelerates muscle regeneration and ameliorates muscular dystrophy by targeting Pax7 in mice

7 Jul 2015

Abstract excerpt

Skeletal muscle stem cells, called satellite cells, are a quiescent heterogeneous population. Their heterogeneity is influenced by Pax7, a well-defined transcriptional regulator of satellite cell functions that defines two subpopulations: Pax7Hi and Pax7Lo. However, the mechanisms by which these subpopulations are established and maintained during myogenesis are not completely understood. Here we show that...

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PMID: 26151913
DOI: 10.1038/ncomms8713

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