Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impaired regeneration in LGMD2A supported by increased PAX7‐positive satellite cell content and muscle‐specific microrna dysregulation

7 Sept 2012

Abstract excerpt

INTRODUCTION: Recent in vitro studies suggest that CAPN3 deficiency leads initially to accelerated myofiber formation followed by depletion of satellite cells (SC). In normal muscle, up-regulation of miR-1 and miR-206 facilitates transition from proliferating SCs to differentiating myogenic progenitors. METHODS: We examined the histopathological stages, Pax7 SC content, and muscle-specific microRNA expression in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammatory Myopathies and Dermatomyositis
Share to Muscle Physiology and Disorders
Share to Skin Diseases and Diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23553538
DOI: 10.1002/mus.23669

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impaired regeneration in LGMD2A supported by increased PAX7‐positive satellite cell content and muscle‐specific microrna dysregulationPMID 23553538Read ↗

Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacitySemantic proximity Read ↗

Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacitySemantic proximity Read ↗

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathiesSemantic proximity Read ↗

Single‐cell RNA‐seq reveals novel interaction between muscle satellite cells and fibro‐adipogenic progenitors mediated with FGF7 signallingSemantic proximity Read ↗

Defining and identifying satellite cell-opathies within muscular dystrophies and myopathies.Semantic proximity Read ↗

Single cell RNA sequencing of human FAPs reveals different functional stages in Duchenne muscular dystrophySemantic proximity Read ↗

Spatial and Multiomic profiling of muscle regeneration dynamics in Duchenne Muscular DystrophySemantic proximity Read ↗

Beyond the bulk: overview and novel insights into the dynamics of muscle satellite cells during muscle regenerationSemantic proximity Read ↗

Skeletal muscle in health and diseaseSemantic proximity Read ↗

Cellular pathogenesis of Duchenne muscular dystrophy: progressive myofibre degeneration, chronic inflammation, reactive myofibrosis and satellite cell dysfunctionSemantic proximity Read ↗

Decoding Duchenne muscular dystrophy transcriptome to single nuclei level reveals clinical-genetic correlationsSemantic proximity Read ↗

Patient-specific iPSC-derived cellular models of LGMDR1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.