Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential miRNA Profiling Reveals miR-4433a-5p as a Key Regulator of Chronic Obstructive Pulmonary Disease Progression via PIK3R2- mediated Phenotypic Modulation.

Combinatorial chemistry & high throughput screening - 1 Jan 2024

Tao Siming, Liao Chunyan, Wang Yide, Xu Dan, Li Zheng, Li Fengsen

Abstract excerpt

OBJECTIVE: In this study, a high-throughput sequencing technology was used to screen the differentially expressed miRNA in the patients with "fast" and "slow" progression of chronic obstructive pulmonary disease (COPD). Moreover, the possible mechanism affecting the progression of COPD was preliminarily analyzed based on the target genes of candidate miRNAs. METHODS: The "fast" progressive COPD group included 6...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to MicroRNAs

Share to Phenotype

Share to Phosphatidylinositol 3-Kinases

Share to Pulmonary Disease, Chronic Obstructive

Source

Open in PubMed Open full text

Identifiers

PMID: 38178680
DOI: 10.2174/0113862073243966231030093213
PMCID: PMC11348472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential miRNA Profiling Reveals miR-4433a-5p as a Key Regulator of Chronic Obstructive Pulmonary Disease Progression via PIK3R2- mediated Phenotypic Modulation.PMID 38178680Read ↗

Bioinformatics-based identification of potential microRNA biomarkers in frequent and non-frequent exacerbators of COPD.Semantic proximity Read ↗

MiR-4458 Regulates Autophagy and Apoptosis By Targeting P53 In Chronic Obstructive Pulmonary Disease.Semantic proximity Read ↗

Peripheral leukocyte microRNAs as novel biomarkers for COPD.Semantic proximity Read ↗

Circulating miRNA Profiles Associated with Lung Function DeclineSemantic proximity Read ↗

Construction of Potential miRNA–mRNA Regulatory Network in COPD Plasma by Bioinformatics AnalysisSemantic proximity Read ↗

Bioinformatic analysis of microRNA and mRNA Regulation in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary diseaseSemantic proximity Read ↗

Identification of common microRNA between COPD and non-small cell lung cancer through pathway enrichment analysisSemantic proximity Read ↗

Genome-Wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer DevelopmentSemantic proximity Read ↗

Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha1-antitrypsin deficiency.Semantic proximity Read ↗

Plasma mi RNAs might be promising biomarkers of chronic obstructive pulmonary diseaseSemantic proximity Read ↗

microRNA–mRNA regulatory networks underlying chronic mucus hypersecretion in COPDSemantic proximity Read ↗

Differential Expression of MicroRNAs in Chronic Obstructive Pulmonary Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.